St John's Primary School originated as an initiative of the people of St John's Catholic Parish, Euroa who saw a need for a primary school for the children of the area founded in the Catholic traditions . Their vision was one where all children had the opportunity to access a Catholic Education for years to come.

The school was built entirely from the labour and generosity of parishioners since government grants for Catholic Schools did not exist at that time. The school opened in 1921. The Sisters of Mercy formed the first teaching staff and continued to be a guiding presence in the school for many many years.  Their Charism continues on today through the school’s vision statement, the school logo featuring the Mercy cross and the naming of the Mercy Centre.  In 2021 the school celebrated its Centenary and all the wonderful learning that has taken place over the past 100 years.